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Electrophysiological Properties of Motor Neurons in a Mouse Model of Severe Spinal Muscular Atrophy: In Vitro versus In Vivo Development

We examined the electrophysiological activity of motor neurons from the mouse model of severe spinal muscular atrophy (SMA) using two different methods: whole cell patch clamp of neurons cultured from day 13 embryos; and multi-electrode recording of ventral horns in spinal cord slices from pups on p...

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Detalles Bibliográficos
Autores principales: Zhang, Hongmei, Robinson, Natallia, Wu, Chiayen, Wang, Wenlan, Harrington, Melissa A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908141/
https://www.ncbi.nlm.nih.gov/pubmed/20657731
http://dx.doi.org/10.1371/journal.pone.0011696