B Cell Activating Factor (BAFF) and T Cells Cooperate to Breach B Cell Tolerance in Lupus-Prone New Zealand Black (NZB) Mice

The presence of autoantibodies in New Zealand Black (NZB) mice suggests a B cell tolerance defect however the nature of this defect is unknown. To determine whether defects in B cell anergy contribute to the autoimmune phenotype in NZB mice, soluble hen egg lysozyme (sHEL) and anti-HEL Ig transgenes...

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Detalles Bibliográficos
Autores principales: Chang, Nan-Hua, Cheung, Yui-Ho, Loh, Christina, Pau, Evelyn, Roy, Valerie, Cai, Yong-Chun, Wither, Joan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908288/
https://www.ncbi.nlm.nih.gov/pubmed/20661465
http://dx.doi.org/10.1371/journal.pone.0011691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908288/
https://www.ncbi.nlm.nih.gov/pubmed/20661465
http://dx.doi.org/10.1371/journal.pone.0011691

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