Structural Convergence Among Diverse, Toxic β-Sheet Ion Channels

[Image: see text] Recent studies show that an array of β-sheet peptides, including N-terminally truncated Aβ peptides (Aβ(11−42/17−42)), K3 (a β(2)-microglobulin fragment), and protegrin-1 (PG-1) peptides form ion channel-like structures and elicit single channel ion conductance when reconstituted i...

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Detalles Bibliográficos
Autores principales: Jang, Hyunbum, Teran Arce, Fernando, Ramachandran, Srinivasan, Capone, Ricardo, Lal, Ratnesh, Nussinov, Ruth
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908347/
https://www.ncbi.nlm.nih.gov/pubmed/20608696
http://dx.doi.org/10.1021/jp104073k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908347/
https://www.ncbi.nlm.nih.gov/pubmed/20608696
http://dx.doi.org/10.1021/jp104073k

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