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Structural Convergence Among Diverse, Toxic β-Sheet Ion Channels
[Image: see text] Recent studies show that an array of β-sheet peptides, including N-terminally truncated Aβ peptides (Aβ(11−42/17−42)), K3 (a β(2)-microglobulin fragment), and protegrin-1 (PG-1) peptides form ion channel-like structures and elicit single channel ion conductance when reconstituted i...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908347/ https://www.ncbi.nlm.nih.gov/pubmed/20608696 http://dx.doi.org/10.1021/jp104073k |