Copy number, linkage disequilibrium and disease association in the FCGR locus

The response of a leukocyte to immune complexes (ICs) is modulated by receptors for the Fc region of IgG (FcγRs), and alterations in their affinity or function have been associated with risk of autoimmune diseases, including systemic lupus erythematosus (SLE). The low-affinity FcγR genomic locus is...

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Detalles Bibliográficos
Autores principales: Niederer, Heather A., Willcocks, Lisa C., Rayner, Tim F., Yang, Wanling, Lau, Yu Lung, Williams, Thomas N., Scott, J. Anthony G., Urban, Britta C., Peshu, Norbert, Dunstan, Sarah J., Hien, Tran Tinh, Phu, Nguyen Hoan, Padyukov, Leonid, Gunnarsson, Iva, Svenungsson, Elisabet, Savage, Caroline O., Watts, Richard A., Lyons, Paul A., Clayton, David G., Smith, Kenneth G.C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Association Studies Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908468/
https://www.ncbi.nlm.nih.gov/pubmed/20508037
http://dx.doi.org/10.1093/hmg/ddq216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908468/
https://www.ncbi.nlm.nih.gov/pubmed/20508037
http://dx.doi.org/10.1093/hmg/ddq216

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