Tumor-Derived Microvesicles Induce, Expand and Up-Regulate Biological Activities of Human Regulatory T Cells (Treg)

BACKGROUND: Tumor-derived microvesicles (TMV) or exosomes are present in body fluids of patients with cancer and might be involved in tumor progression. The frequency and suppressor functions of peripheral blood CD4(+)CD25(high)FOXP3(+) Treg are higher in patients with cancer than normal controls. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Szajnik, Marta, Czystowska, Malgorzata, Szczepanski, Miroslaw J., Mandapathil, Magis, Whiteside, Theresa L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908536/
https://www.ncbi.nlm.nih.gov/pubmed/20661468
http://dx.doi.org/10.1371/journal.pone.0011469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908536/
https://www.ncbi.nlm.nih.gov/pubmed/20661468
http://dx.doi.org/10.1371/journal.pone.0011469

Ejemplares similares