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Neurod1 Suppresses Hair Cell Differentiation in Ear Ganglia and Regulates Hair Cell Subtype Development in the Cochlea

BACKGROUND: At least five bHLH genes regulate cell fate determination and differentiation of sensory neurons, hair cells and supporting cells in the mammalian inner ear. Cross-regulation of Atoh1 and Neurog1 results in hair cell changes in Neurog1 null mice although the nature and mechanism of the c...

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Detalles Bibliográficos
Autores principales: Jahan, Israt, Pan, Ning, Kersigo, Jennifer, Fritzsch, Bernd
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908541/
https://www.ncbi.nlm.nih.gov/pubmed/20661473
http://dx.doi.org/10.1371/journal.pone.0011661