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Susceptible cell lines for the production of porcine reproductive and respiratory syndrome virus by stable transfection of sialoadhesin and CD163

BACKGROUND: Porcine reproductive and respiratory syndrome virus (PRRSV) causes major economic losses in the pig industry worldwide. In vivo, the virus infects a subpopulation of tissue macrophages. In vitro, PRRSV only replicates in primary pig macrophages and African green monkey kidney derived cel...

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Detalles Bibliográficos
Autores principales: Delrue, Iris, Van Gorp, Hanne, Van Doorsselaere, Jan, Delputte, Peter L, Nauwynck, Hans J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908558/
https://www.ncbi.nlm.nih.gov/pubmed/20587060
http://dx.doi.org/10.1186/1472-6750-10-48