Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers

BACKGROUND: The tumor suppressor pRb plays a key role regulating cell cycle arrest, and disturbances in the RB1 gene have been reported in different cancer forms. However, the literature reports contradictory findings with respect to a pro - versus anti - apoptotic role of pRb, and the consequence o...

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Detalles Bibliográficos
Autores principales: Berge, Elisabet Ognedal, Knappskog, Stian, Geisler, Stephanie, Staalesen, Vidar, Pacal, Marec, Børresen-Dale, Anne-Lise, Puntervoll, Pål, Lillehaug, Johan Richard, Lønning, Per Eystein
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908580/
https://www.ncbi.nlm.nih.gov/pubmed/20594292
http://dx.doi.org/10.1186/1476-4598-9-173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908580/
https://www.ncbi.nlm.nih.gov/pubmed/20594292
http://dx.doi.org/10.1186/1476-4598-9-173

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