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Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers
BACKGROUND: The tumor suppressor pRb plays a key role regulating cell cycle arrest, and disturbances in the RB1 gene have been reported in different cancer forms. However, the literature reports contradictory findings with respect to a pro - versus anti - apoptotic role of pRb, and the consequence o...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908580/ https://www.ncbi.nlm.nih.gov/pubmed/20594292 http://dx.doi.org/10.1186/1476-4598-9-173 |