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A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients

BACKGROUND: Hypoxia is a condition of low oxygen tension occurring in the tumor microenvironment and it is related to poor prognosis in human cancer. To examine the relationship between hypoxia and neuroblastoma, we generated and tested an in vitro derived hypoxia gene signature for its ability to p...

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Detalles Bibliográficos
Autores principales: Fardin, Paolo, Barla, Annalisa, Mosci, Sofia, Rosasco, Lorenzo, Verri, Alessandro, Versteeg, Rogier, Caron, Huib N, Molenaar, Jan J, Øra, Ingrid, Eva, Alessandra, Puppo, Maura, Varesio, Luigi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908582/
https://www.ncbi.nlm.nih.gov/pubmed/20624283
http://dx.doi.org/10.1186/1476-4598-9-185