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Oseltamivir-Resistant Pandemic A/H1N1 Virus Is as Virulent as Its Wild-Type Counterpart in Mice and Ferrets

The neuraminidase inhibitor oseltamivir is currently used for treatment of patients infected with the pandemic A/H1N1 (pH1N1) influenza virus, although drug-resistant mutants can emerge rapidly and possibly be transmitted. We describe the characteristics of a pair of oseltamivir-resistant and oselta...

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Detalles Bibliográficos
Autores principales: Hamelin, Marie-Ève, Baz, Mariana, Abed, Yacine, Couture, Christian, Joubert, Philippe, Beaulieu, Édith, Bellerose, Nathalie, Plante, Martin, Mallett, Corey, Schumer, Gregg, Kobinger, Gary P., Boivin, Guy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908621/
https://www.ncbi.nlm.nih.gov/pubmed/20661429
http://dx.doi.org/10.1371/journal.ppat.1001015