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In Vivo Delivery of Gremlin siRNA Plasmid Reveals Therapeutic Potential against Diabetic Nephropathy by Recovering Bone Morphogenetic Protein-7

Diabetic nephropathy is a complex and poorly understood disease process, and our current treatment options are limited. It remains critical, then, to identify novel therapeutic targets. Recently, a developmental protein and one of the bone morphogenetic protein antagonists, Gremlin, has emerged as a...

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Detalles Bibliográficos
Autores principales: Zhang, Qingxian, Shi, Yonghong, Wada, Jun, Malakauskas, Sandra M., Liu, Maodong, Ren, Yunzhuo, Du, Chunyang, Duan, Huijun, Li, Yingmin, Li, Ying, Zhang, Yanling
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908623/
https://www.ncbi.nlm.nih.gov/pubmed/20661431
http://dx.doi.org/10.1371/journal.pone.0011709