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Human Antigen-Specific Regulatory T Cells Generated by T Cell Receptor Gene Transfer

BACKGROUND: Therapies directed at augmenting regulatory T cell (Treg) activities in vivo as a systemic treatment for autoimmune disorders and transplantation may be associated with significant off-target effects, including a generalized immunosuppression that may compromise beneficial immune respons...

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Detalles Bibliográficos
Autores principales: Brusko, Todd M., Koya, Richard C., Zhu, Shirley, Lee, Michael R., Putnam, Amy L., McClymont, Stephanie A., Nishimura, Michael I., Han, Shuhong, Chang, Lung-Ji, Atkinson, Mark A., Ribas, Antoni, Bluestone, Jeffrey A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908680/
https://www.ncbi.nlm.nih.gov/pubmed/20668510
http://dx.doi.org/10.1371/journal.pone.0011726