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Adhesion and Degranulation Promoting Adapter Protein (ADAP) Is a Central Hub for Phosphotyrosine-Mediated Interactions in T Cells

TCR stimulation leads to an increase in cellular adhesion among other outcomes. The adhesion and degranulation promoting adapter protein (ADAP) is known to be rapidly phosphorylated after T cell stimulation and relays the TCR signal to adhesion molecules of the integrin family. While three tyrosine...

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Detalles Bibliográficos
Autores principales: Sylvester, Marc, Kliche, Stefanie, Lange, Sabine, Geithner, Sabine, Klemm, Clementine, Schlosser, Andreas, Großmann, Arndt, Stelzl, Ulrich, Schraven, Burkhart, Krause, Eberhard, Freund, Christian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908683/
https://www.ncbi.nlm.nih.gov/pubmed/20661443
http://dx.doi.org/10.1371/journal.pone.0011708