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Inter- and Intra-Individual Variation in Allele-Specific DNA Methylation and Gene Expression in Children Conceived using Assisted Reproductive Technology

Epidemiological studies have reported a higher incidence of rare disorders involving imprinted genes among children conceived using assisted reproductive technology (ART), suggesting that ART procedures may be disruptive to imprinted gene methylation patterns. We examined intra- and inter-individual...

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Detalles Bibliográficos
Autores principales: Turan, Nahid, Katari, Sunita, Gerson, Leigh F., Chalian, Raffi, Foster, Michael W., Gaughan, John P., Coutifaris, Christos, Sapienza, Carmen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908687/
https://www.ncbi.nlm.nih.gov/pubmed/20661447
http://dx.doi.org/10.1371/journal.pgen.1001033