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HIV-1 Inhibits Autophagy in Bystander Macrophage/Monocytic Cells through Src-Akt and STAT3

Autophagy is a homeostatic mechanism of lysosomal degradation. Defective autophagy has been linked to various disorders such as impaired control of pathogens and neurodegeneration. Autophagy is regulated by a complex array of signaling pathways that act upstream of autophagy proteins. Little is know...

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Detalles Bibliográficos
Autores principales: Van Grol, Jennifer, Subauste, Cecilia, Andrade, Rosa M., Fujinaga, Koh, Nelson, Julie, Subauste, Carlos S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908694/
https://www.ncbi.nlm.nih.gov/pubmed/20661303
http://dx.doi.org/10.1371/journal.pone.0011733