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Distinct Patterns of Expression and Evolution of Intronless and Intron-Containing Mammalian Genes

Comparison of expression levels and breadth and evolutionary rates of intronless and intron-containing mammalian genes shows that intronless genes are expressed at lower levels, tend to be tissue specific, and evolve significantly faster than spliced genes. By contrast, monomorphic spliced genes tha...

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Detalles Bibliográficos
Autores principales: Shabalina, Svetlana A., Ogurtsov, Aleksey Y., Spiridonov, Alexey N., Novichkov, Pavel S., Spiridonov, Nikolay A., Koonin, Eugene V.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908711/
https://www.ncbi.nlm.nih.gov/pubmed/20360214
http://dx.doi.org/10.1093/molbev/msq086