A novel statin-mediated “prenylation block-and-release” assay provides insight into the membrane targeting mechanisms of small GTPases

Ras super-family small GTPases regulate diverse cellular processes such as vesicular transport and signal transduction. Critical to these activities is the ability of these proteins to target to specific intracellular membranes. To allow association with membranes Ras-related GTPases are post-transl...

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Detalles Bibliográficos
Autores principales: Ali, Bassam R., Nouvel, Ian, Leung, Ka Fai, Hume, Alistair N., Seabra, Miguel C.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908739/
https://www.ncbi.nlm.nih.gov/pubmed/20471365
http://dx.doi.org/10.1016/j.bbrc.2010.05.045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908739/
https://www.ncbi.nlm.nih.gov/pubmed/20471365
http://dx.doi.org/10.1016/j.bbrc.2010.05.045

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