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Pseudomonas aeruginosa Exotoxin A Reduces Chemoresistance of Oral Squamous Carcinoma Cell via Inhibition of Heat Shock Proteins 70 (HSP70)

PURPOSE: Oral squamous carcinoma (OSCC) cells exhibit resistance to chemotherapeutic agent-mediated apoptosis in the late stage of malignancy. Increased levels of heat shock proteins 70 (HSP70) in cancer cells are known to confer resistance to apoptosis. Since recent advances in the understanding of...

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Detalles Bibliográficos
Autores principales: Park, Sang Rye, Lee, Kyoung Duk, Kim, Uk Kyu, Gil, Young Gi, Oh, Kyu Seon, Park, Bong Soo, Kim, Gyoo Cheon
Formato: Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908850/
https://www.ncbi.nlm.nih.gov/pubmed/20635445
http://dx.doi.org/10.3349/ymj.2010.51.5.708