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Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R
BACKGROUND: Cell cycle G2 arrest induced by HIV-1 Vpr is thought to benefit viral proliferation by providing an optimized cellular environment for viral replication and by skipping host immune responses. Even though Vpr-induced G2 arrest has been studied extensively, how Vpr triggers G2 arrest remai...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909154/ https://www.ncbi.nlm.nih.gov/pubmed/20609246 http://dx.doi.org/10.1186/1742-4690-7-59 |