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Common variants in the regulative regions of GRIA1 and GRIA3 receptor genes are associated with migraine susceptibility

BACKGROUND: Glutamate is the principal excitatory neurotransmitter in the central nervous system which acts by the activation of either ionotropic (AMPA, NMDA and kainate receptors) or G-protein coupled metabotropic receptors. Glutamate is widely accepted to play a major role in the path physiology...

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Detalles Bibliográficos
Autores principales: Formicola, Daniela, Aloia, Andrea, Sampaolo, Simone, Farina, Olimpia, Diodato, Daria, Griffiths, Lyn R, Gianfrancesco, Fernando, Di Iorio, Giuseppe, Esposito, Teresa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909201/
https://www.ncbi.nlm.nih.gov/pubmed/20579352
http://dx.doi.org/10.1186/1471-2350-11-103