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Ataxin-3 Plays a Role in Mouse Myogenic Differentiation through Regulation of Integrin Subunit Levels

BACKGROUND: During myogenesis several transcription factors and regulators of protein synthesis and assembly are rapidly degraded by the ubiquitin-proteasome system (UPS). Given the potential role of the deubiquitinating enzyme (DUB) ataxin-3 in the UPS, and the high expression of the murine ataxin-...

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Detalles Bibliográficos
Autores principales: Costa, Maria do Carmo, Bajanca, Fernanda, Rodrigues, Ana-João, Tomé, Ricardo J., Corthals, Garry, Macedo-Ribeiro, Sandra, Paulson, Henry L., Logarinho, Elsa, Maciel, Patrícia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909204/
https://www.ncbi.nlm.nih.gov/pubmed/20668528
http://dx.doi.org/10.1371/journal.pone.0011728