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Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer

BACKGROUND: The role of TNFα in cancer is complex with both pro-tumourigenic and anti-tumourigenic roles proposed. We hypothesised that anatomical microlocalisation is critical for its function. METHODS: This study used immunohistochemistry to investigate the expression of TNFα in the tumour islets...

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Detalles Bibliográficos
Autores principales: Ohri, Chandra M, Shikotra, Aarti, Green, Ruth H, Waller, David A, Bradding, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909205/
https://www.ncbi.nlm.nih.gov/pubmed/20573209
http://dx.doi.org/10.1186/1471-2407-10-323