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Innate Immune Suppression Enables Frequent Transfection with RNA Encoding Reprogramming Proteins
BACKGROUND: Generating autologous pluripotent stem cells for therapeutic applications will require the development of efficient DNA-free reprogramming techniques. Transfecting cells with in vitro-transcribed, protein-encoding RNA is a straightforward method of directly expressing high levels of repr...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909252/ https://www.ncbi.nlm.nih.gov/pubmed/20668695 http://dx.doi.org/10.1371/journal.pone.0011756 |