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A Novel Mechanism of Soluble HLA-G Mediated Immune Modulation: Downregulation of T Cell Chemokine Receptor Expression and Impairment of Chemotaxis

BACKGROUND: In recent years, many immunoregulatory functions have been ascribed to soluble HLA-G (sHLA-G). Since chemotaxis is crucial for an efficient immune response, we have investigated for the first time the effects of sHLA-G on chemokine receptor expression and function in different human T ce...

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Detalles Bibliográficos
Autores principales: Morandi, Fabio, Ferretti, Elisa, Bocca, Paola, Prigione, Ignazia, Raffaghello, Lizzia, Pistoia, Vito
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909260/
https://www.ncbi.nlm.nih.gov/pubmed/20668702
http://dx.doi.org/10.1371/journal.pone.0011763