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TIMP-2 Modulates VEGFR-2 Phosphorylation and Enhances Phosphodiesterase Activity in Endothelial Cells

In the present study we examine the effects of tissue inhibitor of metalloproteinases-2 (TIMP-2) on the phosphorylation status of specific phosphotyrosine residues on the vascular endothelial cell growth factor receptor-2 (VEGFR-2) cytoplasmic tail and examine the effects on associated downstream si...

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Detalles Bibliográficos
Autores principales: Lee, Seo-Jin, Tsang, Patricia, Diaz, Tere, Wei, Bei-yang, Stetler-Stevenson, William George
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909682/
https://www.ncbi.nlm.nih.gov/pubmed/20084057
http://dx.doi.org/10.1038/labinvest.2009.136