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Finding Biomarker Signatures in Pooled Sample Designs: A Simulation Framework for Methodological Comparisons
Detection of discriminating patterns in gene expression data can be accomplished by using various methods of statistical learning. It has been proposed that sample pooling in this context would have negative effects; however, pooling cannot always be avoided. We propose a simulation framework to exp...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909718/ https://www.ncbi.nlm.nih.gov/pubmed/20671968 http://dx.doi.org/10.1155/2010/318573 |