Minocycline is cytoprotective in human trabecular meshwork cells and optic nerve head astrocytes by increasing expression of XIAP, survivin, and Bcl-2

INTRODUCTION: Primary open-angle glaucoma (POAG) is one of the leading causes of blindness. Activation of optic nerve head astrocytes (ONHA) and loss of trabecular meshwork cells (TMC) are pathognomonic for this neurodegenerative disease. Oxidative stress and elevated levels of transforming growth f...

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Detalles Bibliográficos
Autores principales: Kernt, Marcus, Neubauer, Aljoscha S, Eibl, Kirsten H, Wolf, Armin, Ulbig, Michael W, Kampik, Anselm, Hirneiss, Cristoph
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909888/
https://www.ncbi.nlm.nih.gov/pubmed/20668721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909888/
https://www.ncbi.nlm.nih.gov/pubmed/20668721

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