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A General Model for Multilocus Epistatic Interactions in Case-Control Studies
BACKGROUND: Epistasis, i.e., the interaction of alleles at different loci, is thought to play a central role in the formation and progression of complex diseases. The complexity of disease expression should arise from a complex network of epistatic interactions involving multiple genes. METHODOLOGY:...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909900/ https://www.ncbi.nlm.nih.gov/pubmed/20814428 http://dx.doi.org/10.1371/journal.pone.0011384 |