A General Model for Multilocus Epistatic Interactions in Case-Control Studies

BACKGROUND: Epistasis, i.e., the interaction of alleles at different loci, is thought to play a central role in the formation and progression of complex diseases. The complexity of disease expression should arise from a complex network of epistatic interactions involving multiple genes. METHODOLOGY:...

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Detalles Bibliográficos
Autores principales: Wang, Zhong, Liu, Tian, Lin, Zhenwu, Hegarty, John, Koltun, Walter A., Wu, Rongling
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909900/
https://www.ncbi.nlm.nih.gov/pubmed/20814428
http://dx.doi.org/10.1371/journal.pone.0011384

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