Influenza Infectious Dose May Explain the High Mortality of the Second and Third Wave of 1918–1919 Influenza Pandemic

BACKGROUND: It is widely accepted that the shift in case-fatality rate between waves during the 1918 influenza pandemic was due to a genetic change in the virus. In animal models, the infectious dose of influenza A virus was associated to the severity of disease which lead us to propose a new hypoth...

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Detalles Bibliográficos
Autores principales: Paulo, A. Cristina, Correia-Neves, Margarida, Domingos, Tiago, Murta, Alberto G., Pedrosa, Jorge
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909907/
https://www.ncbi.nlm.nih.gov/pubmed/20668679
http://dx.doi.org/10.1371/journal.pone.0011655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909907/
https://www.ncbi.nlm.nih.gov/pubmed/20668679
http://dx.doi.org/10.1371/journal.pone.0011655

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