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Distinct Pools of cdc25C Are Phosphorylated on Specific TP Sites and Differentially Localized in Human Mitotic Cells

BACKGROUND: The dual specificity phosphatase cdc25C was the first human cdc25 family member found to be essential in the activation of cdk1/cyclin B1 that takes place at the entry into mitosis. Human cdc25C is phosphorylated on Proline-dependent SP and TP sites when it becomes active at mitosis and...

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Detalles Bibliográficos
Autores principales: Franckhauser, Celine, Mamaeva, Daria, Heron-Milhavet, Lisa, Fernandez, Anne, Lamb, Ned J. C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909920/
https://www.ncbi.nlm.nih.gov/pubmed/20668692
http://dx.doi.org/10.1371/journal.pone.0011798