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Novel O-palmitolylated beta-E1 subunit of pyruvate dehydrogenase is phosphorylated during ischemia/reperfusion injury

BACKGROUND: During and following myocardial ischemia, glucose oxidation rates are low and fatty acids dominate as a source of oxidative metabolism. This metabolic phenotype is associated with contractile dysfunction during reperfusion. To determine the mechanism of this reliance on fatty acid oxidat...

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Detalles Bibliográficos
Autores principales: Folmes, Clifford DL, Sawicki, Grzegorz, Cadete, Virgilio JJ, Masson, Grant, Barr, Amy J, Lopaschuk, Gary D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909933/
https://www.ncbi.nlm.nih.gov/pubmed/20618950
http://dx.doi.org/10.1186/1477-5956-8-38