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Integrin αvβ5 is a primary receptor for adenovirus in CAR-negative cells

BACKGROUND: Viruses bind to specific cellular receptors in order to infect their hosts. The specific receptors a virus uses are important factors in determining host range, cellular tropism, and pathogenesis. For adenovirus, the existing model of entry requires two receptor interactions. First, the...

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Detalles Bibliográficos
Autores principales: Lyle, Cynthia, McCormick, Frank
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909962/
https://www.ncbi.nlm.nih.gov/pubmed/20615244
http://dx.doi.org/10.1186/1743-422X-7-148