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Loss of the SIN3 transcriptional corepressor results in aberrant mitochondrial function

BACKGROUND: SIN3 is a transcriptional repressor protein known to regulate many genes, including a number of those that encode mitochondrial components. RESULTS: By monitoring RNA levels, we find that loss of SIN3 in Drosophila cultured cells results in up-regulation of not only nuclear encoded mitoc...

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Detalles Bibliográficos
Autores principales: Barnes, Valerie L, Strunk, Bethany S, Lee, Icksoo, Hüttemann, Maik, Pile, Lori A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909972/
https://www.ncbi.nlm.nih.gov/pubmed/20618965
http://dx.doi.org/10.1186/1471-2091-11-26