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Single-nucleotide polymorphism, linkage disequilibrium and geographic structure in the malaria parasite Plasmodium vivax: prospects for genome-wide association studies

BACKGROUND: The ideal malaria parasite populations for initial mapping of genomic regions contributing to phenotypes such as drug resistance and virulence, through genome-wide association studies, are those with high genetic diversity, allowing for numerous informative markers, and rare meiotic reco...

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Detalles Bibliográficos
Autores principales: Orjuela-Sánchez, Pamela, Karunaweera, Nadira D, da Silva-Nunes, Mônica, da Silva, Natal S, Scopel, Kézia KG, Gonçalves, Raquel M, Amaratunga, Chanaki, Sá, Juliana M, Socheat, Duong, Fairhust, Rick M, Gunawardena, Sharmini, Thavakodirasah, Thuraisamy, Galapaththy, Gawrie LN, Abeysinghe, Rabindra, Kawamoto, Fumihiko, Wirth, Dyann F, Ferreira, Marcelo U
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910014/
https://www.ncbi.nlm.nih.gov/pubmed/20626846
http://dx.doi.org/10.1186/1471-2156-11-65