Kinome-wide interaction modelling using alignment-based and alignment-independent approaches for kinase description and linear and non-linear data analysis techniques

BACKGROUND: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as cancer. Kinase inhibitors have potential for treatment of these diseases. However, current inhibitors interact with a broad v...

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Detalles Bibliográficos
Autores principales: Lapins, Maris, Wikberg, Jarl ES
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910025/
https://www.ncbi.nlm.nih.gov/pubmed/20569422
http://dx.doi.org/10.1186/1471-2105-11-339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910025/
https://www.ncbi.nlm.nih.gov/pubmed/20569422
http://dx.doi.org/10.1186/1471-2105-11-339

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