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Processive translocation mechanism of the human Bloom’s syndrome helicase along single-stranded DNA
BLM, one of the human RecQ helicases, plays a fundamental role in homologous recombination-based error-free DNA repair pathways, which require its translocation and DNA unwinding activities. Although translocation is essential in vivo during DNA repair processes and it provides a framework for more...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910040/ https://www.ncbi.nlm.nih.gov/pubmed/20211839 http://dx.doi.org/10.1093/nar/gkq145 |