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Novel intronic microRNA represses zebrafish myf5 promoter activity through silencing dickkopf-3 gene
A strong, negative cis-element located at the first intron +502/+835 (I300) of zebrafish myf5 has been reported. To elucidate the molecular mechanism underlying this repression network, we microinjected zebrafish single-cell embryos with I300 RNA, resulting in the dramatic reduction of luciferase ac...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910042/ https://www.ncbi.nlm.nih.gov/pubmed/20236986 http://dx.doi.org/10.1093/nar/gkq148 |