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Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction

The human APOBEC3 proteins are DNA cytidine deaminases that impede the replication of many different transposons and viruses. The genes that encode APOBEC3A, APOBEC3B, APOBEC3C, APOBEC3D, APOBEC3F, APOBEC3G and APOBEC3H were generated through relatively recent recombination events. The resulting hig...

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Detalles Bibliográficos
Autores principales: Refsland, Eric W., Stenglein, Mark D., Shindo, Keisuke, Albin, John S., Brown, William L., Harris, Reuben S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910054/
https://www.ncbi.nlm.nih.gov/pubmed/20308164
http://dx.doi.org/10.1093/nar/gkq174