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Cell-type-specific long-range looping interactions identify distant regulatory elements of the CFTR gene

Identification of regulatory elements and their target genes is complicated by the fact that regulatory elements can act over large genomic distances. Identification of long-range acting elements is particularly important in the case of disease genes as mutations in these elements can result in huma...

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Detalles Bibliográficos
Autores principales: Gheldof, Nele, Smith, Emily M., Tabuchi, Tomoko M., Koch, Christoph M., Dunham, Ian, Stamatoyannopoulos, John A., Dekker, Job
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910055/
https://www.ncbi.nlm.nih.gov/pubmed/20360044
http://dx.doi.org/10.1093/nar/gkq175