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Cell-type-specific long-range looping interactions identify distant regulatory elements of the CFTR gene
Identification of regulatory elements and their target genes is complicated by the fact that regulatory elements can act over large genomic distances. Identification of long-range acting elements is particularly important in the case of disease genes as mutations in these elements can result in huma...
Autores principales: | Gheldof, Nele, Smith, Emily M., Tabuchi, Tomoko M., Koch, Christoph M., Dunham, Ian, Stamatoyannopoulos, John A., Dekker, Job |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910055/ https://www.ncbi.nlm.nih.gov/pubmed/20360044 http://dx.doi.org/10.1093/nar/gkq175 |
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