Unusual evolution of a catalytic core element in CCA-adding enzymes

CCA-adding enzymes are polymerases existing in two distinct enzyme classes that both synthesize the C-C-A triplet at tRNA 3′-ends. Class II enzymes (found in bacteria and eukaryotes) carry a flexible loop in their catalytic core required for switching the specificity of the nucleotide binding pocket...

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Detalles Bibliográficos
Autores principales: Hoffmeier, Andrea, Betat, Heike, Bluschke, Alexander, Günther, Robert, Junghanns, Sandy, Hofmann, Hans-Jörg, Mörl, Mario
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910056/
https://www.ncbi.nlm.nih.gov/pubmed/20348137
http://dx.doi.org/10.1093/nar/gkq176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910056/
https://www.ncbi.nlm.nih.gov/pubmed/20348137
http://dx.doi.org/10.1093/nar/gkq176

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