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Computational generation and screening of RNA motifs in large nucleotide sequence pools
Although identification of active motifs in large random sequence pools is central to RNA in vitro selection, no systematic computational equivalent of this process has yet been developed. We develop a computational approach that combines target pool generation, motif scanning and motif screening us...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910066/ https://www.ncbi.nlm.nih.gov/pubmed/20448026 http://dx.doi.org/10.1093/nar/gkq282 |