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Computational generation and screening of RNA motifs in large nucleotide sequence pools

Although identification of active motifs in large random sequence pools is central to RNA in vitro selection, no systematic computational equivalent of this process has yet been developed. We develop a computational approach that combines target pool generation, motif scanning and motif screening us...

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Detalles Bibliográficos
Autores principales: Kim, Namhee, Izzo, Joseph A., Elmetwaly, Shereef, Gan, Hin Hark, Schlick, Tamar
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910066/
https://www.ncbi.nlm.nih.gov/pubmed/20448026
http://dx.doi.org/10.1093/nar/gkq282