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Combination of RNA interference and U1 inhibition leads to increased inhibition of gene expression
RNA interference (RNAi) has been revolutionary for the specific inhibition of gene expression. However, the application of RNAi has been hampered by the fact that many siRNAs induce dose-dependent unwanted secondary effects. Therefore, new methods to increase inhibition of gene expression with low d...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910067/ https://www.ncbi.nlm.nih.gov/pubmed/20427423 http://dx.doi.org/10.1093/nar/gkq299 |