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TANK is a negative regulator of Toll-like receptor signaling and critical for preventing autoimmune nephritis

The intensity and duration of immune responses are controlled by multiple proteins that modulate Toll-like receptor (TLR) signaling. TRAF family member-associated NF-κB activator (TANK) has been implicated in positive regulation of interferon-regulatory factor-3 as well as NF-κB. Here we demonstrate...

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Detalles Bibliográficos
Autores principales: Kawagoe, Tatsukata, Takeuchi, Osamu, Takabatake, Yoshitsugu, Kato, Hiroki, Isaka, Yoshitaka, Tsujimura, Tohru, Akira, Shizuo
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910115/
https://www.ncbi.nlm.nih.gov/pubmed/19668221
http://dx.doi.org/10.1038/ni.1771