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TANK is a negative regulator of Toll-like receptor signaling and critical for preventing autoimmune nephritis
The intensity and duration of immune responses are controlled by multiple proteins that modulate Toll-like receptor (TLR) signaling. TRAF family member-associated NF-κB activator (TANK) has been implicated in positive regulation of interferon-regulatory factor-3 as well as NF-κB. Here we demonstrate...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910115/ https://www.ncbi.nlm.nih.gov/pubmed/19668221 http://dx.doi.org/10.1038/ni.1771 |