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CTCF shapes chromatin by multiple mechanisms: the impact of 20 years of CTCF research on understanding the workings of chromatin

More than 10(9) base pairs of the genome in higher eucaryotes are positioned in the interphase nucleus such that gene activation, gene repression, remote gene regulation by enhancer elements, and reading as well as adjusting epigenetic marks are possible. One important structural and functional comp...

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Detalles Bibliográficos
Autores principales: Ohlsson, Rolf, Bartkuhn, Marek, Renkawitz, Rainer
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910314/
https://www.ncbi.nlm.nih.gov/pubmed/20174815
http://dx.doi.org/10.1007/s00412-010-0262-0