Investigation on the Interactions of NiCR and NiCR-2H with DNA

We report here a biophysical and biochemical approach to determine the differences in interactions of NiCR and NiCR-2H with DNA. Our goal is to determine whether such interactions are responsible for the recently observed differences in their cytotoxicity toward MCF-7 cancer cells. Viscosity measure...

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Detalles Bibliográficos
Autores principales: Chitranshi, Priyanka, Chen, Chang-Nan, Jones, Patrick R., Faridi, Jesika S., Xue, Liang
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910472/
https://www.ncbi.nlm.nih.gov/pubmed/20671951
http://dx.doi.org/10.1155/2010/619436